VetAgro Sup, France
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Early Academic Pursuits:
Isabelle Fourel embarked on her academic journey, earning a Ph.D. in Physico-Chemistry of Biotransformations from the University of Nantes, France. Her specialization laid the groundwork for her subsequent contributions in the field.
Professional Endeavors:
Since 2004, Her integral part of the Wild Rodents Team at VetAgro Sup - University of Lyon. Her role as Project Manager involves overseeing Bioanalysis and Ecotoxicology of rodenticides. Prior to this, from 1993 to 2004, she served as a Design Engineer at ENITIAA, Nantes, where she headed Analytical Development in the Food Science Department.
Contributions and Research Focus:
Her forefront of analytical development, focusing on the bioaccumulation of chiral rodenticides using Chiral-RP-LC-MS/MS. Her expertise extends to the identification and quantification of organic molecules, especially pesticides and drugs, in various biological matrices. Additionally, her research delves into the ecotoxicology of anticoagulant rodenticides.
Accolades and Recognition:
Her significant contributions are reflected in her co-invention of 19 patents as part of the ISI Neoramus project (2013-2018), with 11 patents granted between 2019 and 2035. Her dedication to innovation and intellectual property is evident in the granted patents, showcasing her impact in the field.
Impact and Influence:
Her influence is particularly notable in her role as a project manager and co-inventor of patents related to rodenticides. Her work in LC-MS/MS analytical development and research into the ecotoxicology of rodenticides demonstrates her commitment to addressing environmental challenges and wildlife conservation.
Legacy and Future Contributions:
Her legacy lies in her extensive contributions to the understanding of rodenticide bioaccumulation and ecotoxicology. Her role in co-inventing patents underscores her commitment to advancing methodologies and technologies in the field. Looking forward, her continued focus on bioanalysis and ecotoxicology suggests ongoing dedication to environmental research and protection.
Notable Publications:
Interest of the faecal and plasma matrix for monitoring the exposure of wildlife or domestic animals to anticoagulant rodenticides
Enantiomer fraction evaluation of the four stereoisomers of second-generation anticoagulant rodenticides in biological matrices with polysaccharide-based chiral selectors and liquid chromatography tandem mass spectrometry
Comparative pharmacokinetics of difethialone stereoisomers in male and female rats and mice: development of an intra- and inter-species model to predict the suitable formulation mix
Exposure of predatory and scavenging birds to anticoagulant rodenticides in France: Exploration of data from French surveillance programs
Monitoring the hepatic residues of cis- and trans-diastereoisomers of second generation anticoagulant rodenticides reveals a different bioaccumulation of diastereoisomers in the food chain of the Réunion harrier (Circus maillardi)
Corticosterone mediates telomere length in raptor chicks exposed to chemical mixture
Les causes de mortalité du Gypaète barbu et des autres vautours en France
Differences in teratogenicity of some vitamin K antagonist substances used as human therapeutic or rodenticide are due to major differences in their fate after an oral administration
Mass spectrometry characterization of anticoagulant rodenticides and hydroxyl metabolites
Accidental chlorophacinone exposure of lactating ewes: Clinical follow-up and human health dietary implications