Bruno LAVIOLLE | Produits de santé | Best Researcher Award

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Prof. Bruno LAVIOLLE  –  Produits de santĂ©(Health products) – Best Researcher Award

Alignment with Award Category

Professor Laviolle’s sustained research excellence, commitment to teaching and mentoring, and innovative contributions to clinical pharmacology make him exceptionally well-suited for the Best Researcher Award or a category recognizing Excellence in Translational Research or Methodological Innovation.

CHU de Rennes | France

Profile
scopus

🎓Early Academic Pursuits 

Education and Training

Born with a passion for science and healthcare, Bruno LAVIOLLE, MD, PhD (N° d’ordre : 35/5922; N° RPPS : 10002677705) embarked on a rich and rigorous academic journey in the biomedical sciences. His academic foundations were laid with a Bachelor in Science during 1997-98, encompassing Biostatistics, Informatics and Modelling at Nantes University, alongside Methods in Clinical Epidemiology and Clinical Research, and Cellular Pharmacology, Pharmacogenetics, and Pharmacokinetics at Rennes 1 University. Driven by a commitment to clinical excellence, he obtained a Master’s in Human Science with a specialization in Fundamental and Clinical Pharmacology from Paris 11 University in 2002. In the same year, he also earned a Certificate in Public Health from Rennes 1 University, setting the stage for a multidimensional understanding of medicine and pharmacology. He achieved his Medical Doctor degree in 2003, followed by certification in Clinical Pharmacology and Therapeutic Research in 2004. His thirst for research culminated in a PhD in 2011 and an Accreditation to Supervise Doctoral Research in 2013, both from Rennes 1 University.

💼Professional Endeavors 

Academic Positions

Professor Bruno Laviolle currently holds multiple influential positions. He serves as a Professor of Clinical Pharmacology at Rennes 1 University and Rennes University Hospital, where he is also Director of the Clinical Investigation Centre, Inserm 1414, located at HĂ´pital de Pontchaillou in Rennes, France. His dual affiliation with Inserm UMR_S 1085 (Irset) and the Clinical Investigation Centre (Inserm 1414) underscores his central role in bridging translational research and clinical pharmacology. Through these institutions, he plays a crucial role in developing and managing pharmacological studies, advancing medical therapies, and training future experts in the field.

📚Contributions and Research Focus on Produits de santé(Health products)

Bruno Laviolle’s research lies at the intersection of clinical pharmacology, cardiovascular pharmacology, and clinical investigation methodologies. His work is characterized by robust biostatistical modeling, rigorous methodologies for clinical trials, and deep expertise in pharmacokinetics and pharmacodynamics. He is especially recognized for his efforts in clinical investigations in cardiovascular pharmacology, an area where his contributions have had meaningful impacts on patient care and drug safety. As the Director of Inserm 1414, he spearheads major clinical trials and translational research projects. His commitment to scientific excellence extends into education, where he leads the Master’s Course of Clinical Research at Rennes University. Additionally, he is actively involved in training medical and graduate students in clinical trial methodology, pharmacological modeling, and biostatistics, equipping the next generation of healthcare professionals with vital research competencies.

🏆Accolades and Recognition 

Professor Laviolle’s remarkable career is supported by his membership in esteemed organizations. He is a valued member of the French Society of Pharmacology and Therapeutics, the European Association for Clinical Pharmacology, and the American College of Clinical Pharmacology, where he serves on the education committee. Furthermore, his membership in the French Association of Medical School Teachers of Pharmacology highlights his respected position in the academic community. These affiliations reflect the high regard in which his peers hold his clinical, academic, and research contributions. His dedication to education and public health has earned him numerous accolades and sustained recognition in both national and international medical communities.

🌍 Impact and Influence 

Community Impact

The impact of Bruno Laviolle’s work reverberates through both clinical practice and academic circles. His influence is evident in the curriculum he has helped shape for medical students and Master’s level scholars at Rennes University, particularly in critical reading of scientific publications, clinical biostatistics, and pharmacological modeling. Through his leadership at Inserm 1414, he has directly influenced the design and implementation of critical drug trials and research protocols in France and beyond. His dual expertise in clinical medicine and research methodology has positioned him as a key figure in fostering evidence-based clinical practices, particularly in cardiovascular pharmacology and public health intervention trials.

🔮Legacy and Future Contributions 

As a dedicated academic and clinician, Bruno Laviolle has built a legacy of scientific rigor, mentorship, and interdisciplinary innovation. His role in developing comprehensive training programs in clinical pharmacology will continue to influence future generations of researchers and physicians. His ongoing involvement in methodological education and clinical investigation ensures that his impact will not only persist but grow. Looking forward, Bruno Laviolle remains at the frontier of pharmacological research, aiming to deepen the integration of data-driven approaches in clinical medicine, enhance patient outcomes, and refine the tools of modern pharmacology. His dedication to mentoring doctoral students and contributing to global scientific dialogue guarantees a lasting footprint in the field.

Conclusion

Bruno Laviolle, MD, PhD, exemplifies the ideals of a physician-scientist: one who bridges theory with practice, research with application, and knowledge with teaching. From his early academic strides through a rich tapestry of multidisciplinary education, to his current role as a Professor of Clinical Pharmacology and Director of Inserm 1414, his career is marked by excellence, innovation, and influence. Whether through his leadership in clinical investigation, his involvement in international pharmacological associations, or his passion for education, Professor Laviolle has significantly shaped the modern landscape of clinical pharmacology. His work not only enhances the effectiveness and safety of therapeutic interventions but also inspires a new generation of clinical researchers and pharmacologists in France and around the world.

đź“šPublications

Trends of Publication of Negative Trials Over Time

 Authors: B., Laviolle, Bruno, C., Locher, Clara, J.S., Allain, Jean Sebastien, … É., Bellissant, Éric, F., Naudet, Florian

Journals: Clinical Pharmacology and Therapeutics

Day-to-day dynamics of fetal heart rate variability to detect chorioamnionitis in preterm premature rupture of membranes

Authors: A., Taoum, Aline, G., Carrault, Guy, C., Tesson, Caroline, … B., Laviolle, Bruno, L., Lassel, Linda

Journals: PLoS ONE

Association between humoral serological markers levels and risk of SARS-CoV-2 infection after the primary COVID-19 vaccine course among ANRS0001S COV-POPART cohort participants

Authors: M., Chalouni, Mathieu, P., Loubet, Paul, E., Lhomme, Edouard, … O., Launay, Odile, L., Wittkop, Linda

Journals: BMC Infectious Disease

Development and validation of a community acquired sepsis-worsening score in the adult emergency department: a prospective cohort: the CASC score

Authors: F., Saget, François, A., Maamar, Adel, M., Esvan, Maxime, … N., Peschanski, N., B., Laviolle, Bruno

Journals: BMC Emergency Medicine

silvana alfei | Drug development | Best Researcher Award

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Prof. Dr. silvana alfei – Drug development – Best Researcher Award

Alignment with Award Category

Professor Alfei’s groundbreaking contributions to organic chemistry, nanomedicine, and biomaterials make her a strong candidate for the Best Researcher Award. Her work aligns well with categories such as Excellence in Innovation, given her pioneering research in biodegradable dendrimers, cationic macromolecules, and amphiphilic nano-vesicles. Her editorial and peer-review contributions further highlight her leadership in the scientific community.

Dipartimento di Farmacia, UniversitĂ  di Genova | Italy

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Orcid

Scopus

🎓Early Academic Pursuits 

Education and Training

Silvana Alfei’s academic journey has been marked by excellence in organic chemistry. She is a Professore e Ricercatore in the Settore Scientifico Disciplinare CHEM-05/A – CHIMICA ORGANICA at the UniversitĂ  di Genova. Her expertise in organic chemistry has been shaped through years of rigorous study, research, and teaching. She has obtained national academic qualification (Abilitazione Scientifica Nazionale, ASN) as a second-rank professor with the credentials required for a first-rank professorship. Her foundational academic training laid the groundwork for her career in organic synthesis, macromolecular chemistry, and nanomedicine. Over the years, she has contributed significantly to both theoretical and applied research, making a lasting impact on her field.

💼Professional Endeavors 

Academic Positions

Since 2006, Silvana Alfei has been a faculty member at the Dipartimento di Farmacia, UniversitĂ  di Genova, where she has been the primary instructor for the Organic Chemistry I course in the Pharmaceutical Chemistry and Technology (CTF) program. Between 2019 and 2021, she also taught Organic Chemistry in the Pharmacy program, further demonstrating her dedication to education and mentorship. Beyond her role as a professor, she is actively involved in academic committees and has served as a commissioner for various evaluations within the university. She has also played a vital role in supervising undergraduate and graduate students, fostering the next generation of researchers in organic chemistry and pharmaceutical sciences.

đź“šContributions and Research Focus on Drug development

Silvana Alfei’s research is focused on cutting-edge advancements in organic chemistry, nanomedicine, and polymer sciences. Her primary research areas include: Synthesis of biodegradable neutral dendrimers containing biologically active molecules for applications in nanomedicine. Development of cationic molecules and macromolecules with intrinsic antibacterial and/or antitumor activity, which can also be utilized for drug encapsulation and solubilization. Crosslinked cationic polymers capable of forming hydrogels for biological and environmental applications. Synthesis of amphiphilic nano-vesicles based on triphenylphosphonium, which exhibit both antibacterial and antitumor properties.

🏆Accolades and Recognition 

Silvana Alfei’s research excellence is reflected in her impressive publication record and scientific impact: H-index of 25 (Scopus), demonstrating her influence in the field. 1,998 citations from 1,276 documents, highlighting the relevance of her research. Author of 111 indexed research articles in high-impact journals, collaborating with scientists both in Italy and internationally. One abstract published in Planta Medica, a journal dedicated to medicinal plant research. One book chapter and one translated volume, contributing to the academic dissemination of scientific knowledge. Multiple oral presentations, including three invited speaker presentations at prestigious conferences.

Additionally, she has held editorial roles in leading scientific journals:

  • Guest Editor for special issues of high-impact indexed journals.
  • Editorial Board Member for International Journal of Molecular Sciences (IJMS) and Nanomaterials (MDPI).
  • Active Reviewer with approximately 216 reviews completed, ensuring the quality and rigor of scientific publications.
  • Academic Editor for numerous articles, contributing to the peer-review process in her field.

🌍 Impact and Influence 

Community Impact

Looking ahead, Silvana Alfei’s research will likely continue to shape advancements in nanotechnology, medicinal chemistry, and polymer sciences. Her future contributions may focus on: Developing more efficient drug delivery systems using biodegradable and biocompatible materials. Enhancing antimicrobial strategies through novel cationic macromolecules and nano-vesicles. Expanding collaborations with international research institutions and industry leaders to translate research findings into practical medical applications.

🔮Legacy and Future Contributions 

With a strong academic background, extensive research contributions, and significant teaching experience, Dr. Ali is poised to leave a lasting impact on the field of supply chain management. His ongoing Ph.D. research is expected to yield further insights into digital supply chains and AI integration, potentially influencing industry practices and policy-making. Looking ahead, he aims to expand his research collaborations, contribute to international conferences, and mentor aspiring researchers in the field.

 

Conclusion

Silvana Alfei stands out as a leading researcher and professor in the field of organic chemistry, making significant contributions to nanomedicine, polymer chemistry, and pharmaceutical sciences. With a strong academic background, an impressive research portfolio, and a dedication to mentorship and peer review, she continues to influence the scientific community and contribute to groundbreaking discoveries.

đź“šPublications

Last Fifteen Years of Nanotechnology Application with Our Contribute

Authors: Silvana Alfei; Guendalina Zuccari

Journals: Nanomaterials

Ellagic Acid: A Green Multi-Target Weapon That Reduces Oxidative Stress and Inflammation to Prevent and Improve the Condition of Alzheimer’s Disease

Authors: Silvana Alfei; Guendalina Zuccari

Journals: International Journal of Molecular Sciences

Strongly ROS-Correlated, Time-Dependent, and Selective Antiproliferative Effects of Synthesized Nano Vesicles on BRAF Mutant Melanoma Cells and Their Hyaluronic Acid-Based Hydrogel Formulation

Authors: Silvana Alfei; Guendalina Zuccari; Constantinos M. Athanassopoulos; Cinzia Domenicotti; Barbara Marengo

Journals: International Journal of Molecular Sciences