Wenzhou medical university | China
Author Profile
Early Academic Pursuits 🎓
She originally from Qingxian, Cangzhou, Hebei Province, embarked on her academic journey with a bachelor’s degree in Medical Laboratory Science from the Medical College of Hunan Normal University. Her early education laid a strong foundation in the biological sciences, fostering a deep interest in medical research. This interest propelled her towards advanced studies, leading to her current pursuit of a PhD in Immunology at the prestigious Peking Union Medical College.
Professional Endeavors 💼
Throughout her academic and professional career, she has demonstrated exceptional dedication and skill in the field of immunology and medical diagnostics. Her research has spanned several critical areas, showcasing her versatility and depth of knowledge.
- Research on LKB1 in Macrophage Homeostasis and Self-renewal: Her groundbreaking work in macrophage homeostasis has been pivotal. She discovered that LKB1 is crucial for maintaining metabolic and immune balance within macrophages. Her findings, which highlighted the vulnerability of lungs to infections like Staphylococcus aureus in the absence of LKB1, were published in Frontiers in Immunology (2021, IF=8.786), where she served as a co-first author.
- Research on Autoimmune Diseases and Digestive System Disorders: Her exploration into autoimmune diseases has uncovered novel immune molecules associated with primary biliary cholangitis (PBC) and psoriasis. These findings, published in Microbiology and Immunology (2018, IF=2.962) and Tohoku Journal of Experimental Medicine (2018, IF=2.547), provided new insights into the Th1/Th2/Treg cell immune function. Additionally, her work on the epigenetic regulation of digestive system diseases, published in Clinical Epigenetics (2020, IF=7.259), emphasized the role of DNA methylation.
- Development of Novel Disease Marker Detection Methods Based on SERS Technology: she pioneered a new method for detecting disease markers on exosomes using PEARL-structured SERS probes. This innovative approach was detailed in Chemical Science (2018, IF=9.969) and has gained significant recognition, with 156 citations from leading international journals.
- Bioinformatics Research: Through her analysis of over 400 methylation samples of gastric cancer and melanoma, she established prognostic models and explored m6A regulatory genes’ diagnostic value in melanoma. These studies, resulting in three SCI papers, underscored her expertise in bioinformatics and computational biology.
Contributions and Research Focus on IMMUNOLOGY 📚
Her primary research focuses on autoimmune diseases and tumor immunology, specifically in the discovery of disease diagnostic markers and the development of novel diagnostic methods. Her work in constructing predictive models has been particularly influential. To date, she has published 15 SCI papers, reflecting her prolific contribution to the scientific community.
Accolades and Recognition 🏆
Her achievements have not gone unnoticed. Her work has received acclaim in various high-impact journals, and her innovative methodologies have been widely cited and utilized by other researchers. This recognition speaks volumes about her impact and the respect she commands in the field of immunology and diagnostics.
Impact and Influence 🌍
Her research has had a profound impact on the scientific community and beyond. Her studies on LKB1 have advanced our understanding of macrophage biology, while her work on autoimmune diseases has provided new therapeutic targets. The novel diagnostic methods she developed using SERS technology have the potential to revolutionize how diseases are detected and monitored, making diagnostics more accurate and efficient.
Legacy and Future Contributions 🔮
As she continues her PhD studies, her future contributions are eagerly anticipated. Her work thus far suggests a promising trajectory, with potential breakthroughs in autoimmune disease treatment and tumor immunology. Her legacy will likely include significant advancements in both experimental and computational methods in medical research.